Appbp2^em2Kajim
Endonuclease-mediated Allele Detail

Summary

• Symbol: Appbp2^em2Kajim
• Name: amyloid beta precursor protein binding protein 2; endonuclease-mediated mutation 2, Shingo Kajimura
• MGI ID: MGI:7432685
• Synonyms: Appbp2^em2Cya, Appbp2 S561N
• Gene: Appbp2 Location: Chr11:85082134-85125946 bp, - strand Genetic Position: Chr11, 51.34 cM, cytoband B5
• Alliance: Appbp2^em2Kajim page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Humanized sequence)
• Mutation: Nucleotide substitutions
• CRISPR-targeting the S561N mutation (equivalent to the human SNP in the APPBP2 gene. (J:333058)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Appbp2 Mutation: 31 strains or lines available

References

• Original: J:333058 Wang Q, et al., Post-translational control of beige fat biogenesis by PRDM16 stabilization. Nature. 2022 Sep;609(7925):151-158
• All: 1 reference(s)