Snap25^tm1.1Safi
Targeted Allele Detail

Summary

• Symbol: Snap25^tm1.1Safi
• Name: synaptosomal-associated protein 25; targeted mutation 1.1, Saaid Safieddine
• MGI ID: MGI:7432664
• Synonyms: Snap-25^lox
• Gene: Snap25 Location: Chr2:136555373-136624348 bp, + strand Genetic Position: Chr2, 67.56 cM
• Alliance: Snap25^tm1.1Safi page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:333049
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: A targeting vector was designed in which loxP sites were introduced upstream and downstream of the Snap25 exon 4, and a neo cassette flanked with Frt sites as a selectable marker was introduced downstream of exon 4. Flp recombinase to remove the neo cassette. (J:333049)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Snap25 Mutation: 26 strains or lines available

References

• Original: J:333049 Calvet C, et al., The SNARE protein SNAP-25 is required for normal exocytosis at auditory hair cell ribbon synapses. iScience. 2022 Dec 22;25(12):105628
• All: 1 reference(s)