Cd80^em1Cya
Endonuclease-mediated Allele Detail

Summary

• Symbol: Cd80^em1Cya
• Name: CD80 antigen; endonuclease-mediated mutation 1, Cyagen Biosciences
• MGI ID: MGI:7431527
• Synonyms: B7-1^flox, Cd80^em1(flox)Cya
• Gene: Cd80 Location: Chr16:38277793-38316682 bp, + strand Genetic Position: Chr16, 26.86 cM, cytoband B5
• Alliance: Cd80^em1Cya page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready, No functional change)
• Mutation: Insertion
• CRISPR/Cas9 technology generated a floxed allele. (J:332964)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Cd80 Mutation: 42 strains or lines available

References

• Original: J:332964 Li J, et al., B7-1 mediates podocyte injury and glomerulosclerosis through communication with Hsp90ab1-LRP5-beta-catenin pathway. Cell Death Differ. 2022 Dec;29(12):2399-2416
• All: 1 reference(s)