Ifnar1^em16Tkay
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ifnar1^em16Tkay
• Name: interferon (alpha and beta) receptor 1; endonuclease-mediated mutation 16, Thomas Kay
• MGI ID: MGI:7431299
• Gene: Ifnar1 Location: Chr16:91282126-91304329 bp, + strand Genetic Position: Chr16, 52.98 cM
• Alliance: Ifnar1^em16Tkay page

Mutation origin

• Strain of Origin: NOD/ShiLtJArc

Mutation description

• Allele Type: Endonuclease-mediated (Not Applicable)
• Mutation: Intragenic deletion
• CRISPR/Cas9 technology using gRNA 5GCTCGCTGTCGTGGGCGCGG-3 generated a 5 bp deletion. (J:325263)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ifnar1 Mutation: 59 strains or lines available

References

• Original: J:325263 Jhala G, et al., Interferons limit autoantigen-specific CD8(+) T-cell expansion in the non-obese diabetic mouse. Cell Rep. 2022 Apr 26;39(4):110747
• All: 1 reference(s)