Uap1^em1Jcui
Endonuclease-mediated Allele Detail

Summary

• Symbol: Uap1^em1Jcui
• Name: UDP-N-acetylglucosamine pyrophosphorylase 1; endonuclease-mediated mutation 1, Jun Cui
• MGI ID: MGI:7431139
• Synonyms: Uap1^-
• Gene: Uap1 Location: Chr1:169969507-170002526 bp, - strand Genetic Position: Chr1, 76.84 cM
• Alliance: Uap1^em1Jcui page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Not Specified
• CRISPR-targeting was used to generate the allele. No molecular description was provided. (J:332899)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Uap1 Mutation: 29 strains or lines available

References

• Original: J:332899 Yang S, et al., Metabolic enzyme UAP1 mediates IRF3 pyrophosphorylation to facilitate innate immune response. Mol Cell. 2023 Jan 19;83(2):298-313.e8
• All: 1 reference(s)