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Uap1em1Jcui
Endonuclease-mediated Allele Detail
Summary
Symbol: Uap1em1Jcui
Name: UDP-N-acetylglucosamine pyrophosphorylase 1; endonuclease-mediated mutation 1, Jun Cui
MGI ID: MGI:7431139
Synonyms: Uap1-
Gene: Uap1  Location: Chr1:169969507-170002526 bp, - strand  Genetic Position: Chr1, 76.84 cM
Alliance: Uap1em1Jcui page
Mutation
origin
Strain of Origin:  C57BL/6J
Mutation
description
Allele Type:    Endonuclease-mediated (Null/knockout)
Mutation:    Not Specified
    CRISPR-targeting was used to generate the allele. No molecular description was provided. (J:332899)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Uap1 Mutation:  29 strains or lines available
References
Original:  J:332899 Yang S, et al., Metabolic enzyme UAP1 mediates IRF3 pyrophosphorylation to facilitate innate immune response. Mol Cell. 2023 Jan 19;83(2):298-313.e8
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory