Hoxc13^em1Tchn
Endonuclease-mediated Allele Detail

Summary

• Symbol: Hoxc13^em1Tchn
• Name: homeobox C13; endonuclease-mediated mutation 1, Ting Chen
• MGI ID: MGI:7430708
• Synonyms: Hoxc13 KO
• Gene: Hoxc13 Location: Chr15:102829566-102837249 bp, + strand Genetic Position: Chr15, Syntenic
• Alliance: Hoxc13^em1Tchn page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR/Cas9 genome editing technology was used to generate an intragenic deletion in exon 1. (J:321758)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Hoxc13 Mutation: 13 strains or lines available

References

• Original: J:321758 Xie Y, et al., Hair shaft miniaturization causes stem cell depletion through mechanosensory signals mediated by a Piezo1-calcium-TNF-alpha axis. Cell Stem Cell. 2022 Jan 6;29(1):70-85.e6
• All: 1 reference(s)