Nudt7^em1Rleo
Endonuclease-mediated Allele Detail

Summary

• Symbol: Nudt7^em1Rleo
• Name: nudix hydrolase 7; endonuclease-mediated mutation 1, Roberta Leonardi
• MGI ID: MGI:7428334
• Synonyms: Nudt7^-
• Gene: Nudt7 Location: Chr8:114860314-114881471 bp, + strand Genetic Position: Chr8, 60.53 cM
• Alliance: Nudt7^em1Rleo page

Mutation origin

• Strain of Origin: Not Applicable

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting introduced the deletion of exons 3 and 4 in the Nudt7 gene. (J:332648)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nudt7 Mutation: 15 strains or lines available

References

• Original: J:332648 Vickers SD, et al., NUDT7 regulates total hepatic CoA levels and the composition of the intestinal bile acid pool in male mice fed a Western diet. J Biol Chem. 2022 Nov 24;299(1):102745
• All: 1 reference(s)