Spp1^em1Nnto
Endonuclease-mediated Allele Detail

Summary

• Symbol: Spp1^em1Nnto
• Name: secreted phosphoprotein 1; endonuclease-mediated mutation 1, Natalia Nieto
• MGI ID: MGI:7427736
• Synonyms: Opn^fl
• Gene: Spp1 Location: Chr5:104582984-104588916 bp, + strand Genetic Position: Chr5, 50.68 cM
• Alliance: Spp1^em1Nnto page

Mutation origin

• Strain of Origin: Not Applicable

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready, No functional change)
• Mutation: Insertion
• CRISPR-targeting floxed exons 4 through 7. (J:328256)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Spp1 Mutation: 40 strains or lines available

References

• Original: J:328256 Das S, et al., Intestinal Osteopontin Protects From Alcohol-induced Liver Injury by Preserving the Gut Microbiome and the Intestinal Barrier Function. Cell Mol Gastroenterol Hepatol. 2022 Jul 8
• All: 1 reference(s)