Rnf20^tm1.1Liwe
Targeted Allele Detail

Summary

• Symbol: Rnf20^tm1.1Liwe
• Name: ring finger protein 20; targeted mutation 1.1, Wei Li
• MGI ID: MGI:7427496
• Synonyms: Rnf20^Flox
• Gene: Rnf20 Location: Chr4:49632006-49656887 bp, + strand Genetic Position: Chr4, 26.69 cM
• Alliance: Rnf20^tm1.1Liwe page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:250237
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: The targeting construct floxed exons 2 through 4. Flp-mediated recombination removed the FRT-flanked neomycin resistance cassette inserted downstream of exon 4. (J:250237)

Expression

In Mice Carrying this Mutation:

34 assay results 2 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rnf20 Mutation: 40 strains or lines available

References

• Original: J:250237 Xu Z, et al., H2B ubiquitination regulates meiotic recombination by promoting chromatin relaxation. Nucleic Acids Res. 2016 Nov 16;44(20):9681-9697
• All: 4 reference(s)