Fgf23^tm1.1Mlne
Targeted Allele Detail

Summary

• Symbol: Fgf23^tm1.1Mlne
• Name: fibroblast growth factor 23; targeted mutation 1.1, Maren Leifheit-Nestler
• MGI ID: MGI:7425349
• Synonyms: Fgf23^fl, Fgf23^tm1Mln
• Gene: Fgf23 Location: Chr6:127049865-127058371 bp, + strand Genetic Position: Chr6, 61.92 cM
• Alliance: Fgf23^tm1.1Mlne page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:326344
• Parent Cell Line: iTL BF1 (ES Cell)
• Strain of Origin: C57BL/6NTac

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 2 and an FRT flanked selection cassette and loxP site were inserted downstream of exon 2. Flp mediated recombination removed the selection cassette. (J:326344)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fgf23 Mutation: 19 strains or lines available

References

• Original: J:326344 Eitner F, et al., Comprehensive Expression Analysis of Cardiac Fibroblast Growth Factor 23 in Health and Pressure-induced Cardiac Hypertrophy. Front Cell Dev Biol. 2021;9:791479
• All: 1 reference(s)