Cebpb^em1Ngwu
Endonuclease-mediated Allele Detail

Summary

• Symbol: Cebpb^em1Ngwu
• Name: CCAAT/enhancer binding protein beta; endonuclease-mediated mutation 1, Ning Wu
• MGI ID: MGI:7424951
• Synonyms: C/EBPbeta HA KI
• Gene: Cebpb Location: Chr2:167530835-167532338 bp, + strand Genetic Position: Chr2, 87.58 cM
• Alliance: Cebpb^em1Ngwu page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Epitope tag)
• Mutation: Insertion
• Mutation details: crRNA/tracrRNA duplex gRNA was designed to insert an N-terminal HA tag immediately downstream of the start codon. This insertion is designed to only tag the longest isoform, and has less protein expression. (J:332404)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Cebpb Mutation: 26 strains or lines available

References

• Original: J:332404 Lau KH, et al., PPARgamma and C/EBPalpha response to acute cold stress in brown adipose tissue. iScience. 2023 Jan 20;26(1):105848
• All: 1 reference(s)