Gt(ROSA)26Sor^{tm1(CAG-Foxp1)Huihu}
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^{tm1(CAG-Foxp1)Huihu}
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Hui Hu
• MGI ID: MGI:7424862
• Synonyms: Foxp1a^Tg, Foxp1ECTg
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^{tm1(CAG-Foxp1)Huihu} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:215934
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, Epitope tag, Inserted expressed sequence, Reporter)
• Mutation: Insertion
• Mutation details: A loxP-flanked neo-STOP cassette, Flag-Foxp1a, and frt-flanked IRES-EGFP cassette, and the polyadenylation signal were inserted downstream of the CAG promoter in Gt(ROSA)26Sor locus. (J:215934)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 1084 strains or lines available

References

• Original: J:215934 Wang H, et al., The transcription factor Foxp1 is a critical negative regulator of the differentiation of follicular helper T cells. Nat Immunol. 2014 Jul;15(7):667-75
• All: 5 reference(s)