C1galt1c1^tm1.1Staka
Targeted Allele Detail

Summary

• Symbol: C1galt1c1^tm1.1Staka
• Name: C1GALT1-specific chaperone 1; targeted mutation 1.1, Satoru Takahashi
• MGI ID: MGI:7424861
• Synonyms: Cosmc^flox
• Gene: C1galt1c1 Location: ChrX:37719662-37723964 bp, - strand Genetic Position: ChrX, 22.91 cM, cytoband A2
• Alliance: C1galt1c1^tm1.1Staka page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:271769
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: A loxP site, FRT-flanked PGK-neomycin cassette, and second loxP site were inserted upstream of exon 2 and a third loxP site was inserted downstream of exon 2. The neomycin cassette was removed via flp-mediated recombination leaving exon 2 floxed. (J:271769)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any C1galt1c1 Mutation: 16 strains or lines available

References

• Original: J:271769 Wakui H, et al., Incomplete clearance of apoptotic cells by core 1-derived O-glycan-deficient resident peritoneal macrophages. Biochem Biophys Res Commun. 2018 Jan 8;495(2):2017-2023
• All: 2 reference(s)