Sik2^tm1Pg
Targeted Allele Detail

Summary

• Symbol: Sik2^tm1Pg
• Name: salt inducible kinase 2; targeted mutation 1, PolyGene AG
• MGI ID: MGI:7423839
• Synonyms: SIK2-KO
• Gene: Sik2 Location: Chr9:50804101-50920373 bp, - strand Genetic Position: Chr9, 27.75 cM
• Alliance: Sik2^tm1Pg page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:332352
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Undefined
• A molecular description was not provided. It is a constitutive Sik2 null allele. (J:332352)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Sik2 Mutation: 45 strains or lines available

References

• Original: J:332352 Pires NM, et al., Antagonistic modulation of SIK1 and SIK2 isoforms in high blood pressure and cardiac hypertrophy triggered by high-salt intake. Clin Exp Hypertens. 2021 Jul 4;43(5):428-435
• All: 1 reference(s)