Sirt7^tm1Smoc
Targeted Allele Detail

Summary

• Symbol: Sirt7^tm1Smoc
• Name: sirtuin 7; targeted mutation 1, Shanghai Model Organisms Center
• MGI ID: MGI:7414304
• Synonyms: Sirt7^flox
• Gene: Sirt7 Location: Chr11:120509197-120515840 bp, - strand Genetic Position: Chr11, 84.34 cM
• Alliance: Sirt7^tm1Smoc page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:330780
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• The targeting construct floxed exons 6 through 9. (J:330780)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Sirt7 Mutation: 20 strains or lines available

References

• Original: J:330780 Liu Z, et al., SIRT7 couples light-driven body temperature cues to hepatic circadian phase coherence and gluconeogenesis. Nat Metab. 2019 Nov;1(11):1141-1156
• All: 1 reference(s)