Gt(ROSA)26Sor^{tm2(NGFR)Daav}
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^{tm2(NGFR)Daav}
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Dario AA Vignali
• MGI ID: MGI:7414277
• Synonyms: Rosa26^LSL.hNGFR
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^{tm2(NGFR)Daav} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:312516
• Parent Cell Line: JM8A3.N1 (ES Cell)
• Strain of Origin: C57BL/6N-A^tm1Brd

Mutation description

• Allele Type: Targeted (Conditional ready, Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: Human NGFR was inserted in the ATG start codon within the Rosa26 locus downstream of the LSL cassette. (J:312516)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 1095 strains or lines available

References

• Original: J:312516 Andrews LP, et al., A Cre-driven allele-conditioning line to interrogate CD4(+) conventional T cells. Immunity. 2021 Oct 12;54(10):2209-2217.e6
• All: 1 reference(s)