Tg(Gata3-lacZ)C4Jeng
Transgene Detail

Summary

• Symbol: Tg(Gata3-lacZ)C4Jeng
• Name: transgene insertion C4, James Douglas Engel
• MGI ID: MGI:7413191
• Synonyms: C4lacZ
• Transgene: Tg(Gata3-lacZ)C4Jeng Location: unknown
• Alliance: Tg(Gata3-lacZ)C4Jeng page

Transgene origin

• Strain of Origin: Not Applicable

Transgene description

• Transgene Type: Transgenic (Reporter)
• Mutation: Insertion
• Mutation details: The transgene contains a ~120 kb B1 repeat deletion subfragment of ~485 kb C3H YAC ICRFy903F1113. The YAC contains the entire Gata3 gene plus upstream and downstream regulatory regions and was modified by inserting a lacZ beta-galactosidase reporter gene cassette immediately downstream of (in-frame with) the Gata3 ATG start site. The reporter gene is expressed in many but not all tissues that normally express Gata3 during embryonic development. Seventeen mouse lines were established. (J:51930)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:51930 Lakshmanan G, et al., Partial rescue of GATA-3 by yeast artificial chromosome transgenes. Dev Biol. 1998 Dec 15;204(2):451-63
• All: 2 reference(s)