Fbxo7^tm1.1Noha
Targeted Allele Detail

Summary

• Symbol: Fbxo7^tm1.1Noha
• Name: F-box protein 7; targeted mutation 1.1, Nobutaka Hattori
• MGI ID: MGI:7413185
• Synonyms: Fbxo7^flox
• Gene: Fbxo7 Location: Chr10:85857836-85887737 bp, + strand Genetic Position: Chr10, 41.91 cM
• Alliance: Fbxo7^tm1.1Noha page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:327559
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 3 and an FRT flanked neo cassette and loxP site were inserted downstream of exon 4 via homologous recombination. Flp-mediated recombination removed the neo cassette. (J:327559)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fbxo7 Mutation: 27 strains or lines available

References

• Original: J:327559 Noda S, et al., Impaired mitochondrial accumulation and Lewy pathology in neuron-specific FBXO7-deficient mice. Mol Brain. 2022 Jun 14;15(1):54
• All: 1 reference(s)