Col4a3tm1Dlts
Targeted Allele Detail
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Symbol: |
Col4a3tm1Dlts |
Name: |
collagen, type IV, alpha 3; targeted mutation 1, Constantinos Deltas |
MGI ID: |
MGI:7413121 |
Synonyms: |
Col4a3-G1332E |
Gene: |
Col4a3 Location: Chr1:82564647-82699778 bp, + strand Genetic Position: Chr1, 42.32 cM
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Alliance: |
Col4a3tm1Dlts page
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Germline Transmission: |
Earliest citation of germline transmission:
J:330820
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
Not Specified
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Allele Type: |
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Targeted (Not Specified) |
Mutation: |
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Single point mutation
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Mutation details: The targeting construct replaced exon 45 with an FRT-flanked neomycin resistance cassette and a modified exon 45 encoding the amino acid substitution glycine with glutamic acid at position 1332 (G1332E).
(J:330820)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Col4a3 Mutation: |
60 strains or lines available
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Original: |
J:330820 Pieri M, et al., Evidence for activation of the unfolded protein response in collagen IV nephropathies. J Am Soc Nephrol. 2014 Feb;25(2):260-75 |
All: |
2 reference(s) |
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