Mirc27^em1.1Hhzg
Endonuclease-mediated Allele Detail

Summary

• Symbol: Mirc27^em1.1Hhzg
• Name: microRNA cluster 27, including Mir497 through Mir195a; endonuclease-mediated mutation 1.1, Xiao-yan Zhou
• MGI ID: MGI:7412987
• Gene: Mirc27 Location: unknown Genetic Position: Chr11, Syntenic

Mutation origin

• Strain of Origin: (C57BL/6 x 129S4/SvJae)F1

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• CRISPR-targeting floxed the cluster. Cre-mediated recombination removed the cluster. (J:320883)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mirc27 Mutation: 3 strains or lines available

References

• Original: J:320883 Hutter K, et al., Differential roles of miR-15a/16-1 and miR-497/195 clusters in immune cell development and homeostasis. FEBS J. 2021 Mar;288(5):1533-1545
• All: 1 reference(s)