Sh3rf2^em1Holi
Endonuclease-mediated Allele Detail

Summary

• Symbol: Sh3rf2^em1Holi
• Name: SH3 domain containing ring finger 2; endonuclease-mediated mutation 1, Hongliang Li
• MGI ID: MGI:7411388
• Synonyms: Sh3rf2-flox
• Gene: Sh3rf2 Location: Chr18:42186732-42292025 bp, + strand Genetic Position: Chr18, 22.21 cM
• Alliance: Sh3rf2^em1Holi page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready)
• Mutation: Insertion
• CRISPR/Cas9 technology inserted loxP sites flanking exon 5. (J:332191)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Sh3rf2 Mutation: 54 strains or lines available

References

• Original: J:332191 Yang X, et al., Hepatocyte SH3RF2 Deficiency Is a Key Aggravator for NAFLD. Hepatology. 2021 Sep;74(3):1319-1338
• All: 1 reference(s)