Lnpep^tm1.1Alba
Targeted Allele Detail

Summary

• Symbol: Lnpep^tm1.1Alba
• Name: leucyl/cystinyl aminopeptidase; targeted mutation 1.1, Anthony L Albiston
• MGI ID: MGI:7411313
• Synonyms: IRAP(-)
• Gene: Lnpep Location: Chr17:17747985-17846303 bp, - strand Genetic Position: Chr17, 9.77 cM
• Alliance: Lnpep^tm1.1Alba page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:293044
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A loxP site was inserted upstream of exon 2 and a PGK-neomycin resistance gene and second loxP site were inserted downstream of exon 2. Exon 2 and the selection cassette were removed via cre-mediated recombination. (J:293044)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Lnpep Mutation: 99 strains or lines available

References

• Original: J:293044 Pham V, et al., Reproduction and maternal behavior in insulin-regulated aminopeptidase (IRAP) knockout mice. Peptides. 2009 Oct;30(10):1861-5
• All: 1 reference(s)