Rcan1^em1Bfz
Endonuclease-mediated Allele Detail

Summary

• Symbol: Rcan1^em1Bfz
• Name: regulator of calcineurin 1; endonuclease-mediated mutation 1, Bai-Fang Zhang
• MGI ID: MGI:7411293
• Synonyms: Rcan1^flox
• Gene: Rcan1 Location: Chr16:92188839-92263057 bp, - strand Genetic Position: Chr16, 53.6 cM
• Alliance: Rcan1^em1Bfz page

Mutation origin

• Strain of Origin: Not Applicable

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready, No functional change)
• Mutation: Insertion
• CRISPR-targeting floxed exons 5 and 6. (J:328839, J:330849)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rcan1 Mutation: 24 strains or lines available

References

• Original: J:330849 Xiao JJ, et al., Regulator of calcineurin 1 deletion attenuates mitochondrial dysfunction and apoptosis in acute kidney injury through JNK/Mff signaling pathway. Cell Death Dis. 2022 Sep 7;13(9):774
• All: 2 reference(s)