Uba3^tm1Smoc
Targeted Allele Detail

Summary

• Symbol: Uba3^tm1Smoc
• Name: ubiquitin-like modifier activating enzyme 3; targeted mutation 1, Shanghai Model Organisms Center
• MGI ID: MGI:7411102
• Synonyms: UBA3^F
• Gene: Uba3 Location: Chr6:97160631-97182608 bp, - strand Genetic Position: Chr6, 44.9 cM
• Alliance: Uba3^tm1Smoc page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:325424
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129/SvEv

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 3 and an FRT-flanked neomycin cassette and second loxP site were inserted downstream of exon 3. (J:325424)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Uba3 Mutation: 41 strains or lines available

References

• Original: J:325424 Zhang X, et al., Neddylation is required for herpes simplex virus type I (HSV-1)-induced early phase interferon-beta production. Cell Mol Immunol. 2016 Sep;13(5):578-83
• All: 4 reference(s)