Angptl7^tm2Vlcg
Targeted Allele Detail

Summary

• Symbol: Angptl7^tm2Vlcg
• Name: angiopoietin-like 7; targeted mutation 2, Velocigene
• MGI ID: MGI:7410920
• Gene: Angptl7 Location: Chr4:148579737-148584919 bp, - strand Genetic Position: Chr4, 78.76 cM
• Alliance: Angptl7^tm2Vlcg page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:330870
• Parent Cell Line: VGF1 (ES Cell)
• Strain of Origin: (129S6/SvEvTac x C57BL/6NTac)F1

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The targeting construct ablated 571 bp beginning 153 bp upstream of the start codon and inserted a self-deleting hygromycin selection cassette. (J:330870)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Angptl7 Mutation: 27 strains or lines available

References

• Original: J:330870 Praveen K, et al., ANGPTL7, a therapeutic target for increased intraocular pressure and glaucoma. Commun Biol. 2022 Oct 3;5(1):1051
• All: 1 reference(s)