Hipk2^em2Jxiao
Endonuclease-mediated Allele Detail

Summary

• Symbol: Hipk2^em2Jxiao
• Name: homeodomain interacting protein kinase 2; endonuclease-mediated mutation 2, Junjie Xiao
• MGI ID: MGI:7410919
• Gene: Hipk2 Location: Chr6:38671325-38853099 bp, - strand Genetic Position: Chr6, 17.85 cM, cytoband B
• Alliance: Hipk2^em2Jxiao page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting of exon 2 deleted 40 bp resulting in a frameshift. (J:330872)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Hipk2 Mutation: 53 strains or lines available

References

• Original: J:330872 Zhou Q, et al., Inhibition of HIPK2 protects stress-induced pathological cardiac remodeling. EBioMedicine. 2022 Sep 28;85:104274
• All: 1 reference(s)