Cd5l^em1Tmiy
Endonuclease-mediated Allele Detail

Summary

• Symbol: Cd5l^em1Tmiy
• Name: CD5 antigen-like; endonuclease-mediated mutation 1, Toru Miyazaki
• MGI ID: MGI:7408590
• Synonyms: AIM^-
• Gene: Cd5l Location: Chr3:87265188-87278380 bp, + strand Genetic Position: Chr3, 38.19 cM
• Alliance: Cd5l^em1Tmiy page

Mutation origin

• Strain of Origin: CD-1

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR/Cas9 technology generated a deletion at the first ATG region. (J:315180)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cd5l Mutation: 30 strains or lines available

References

• Original: J:315180 Wang CT, et al., High salt exacerbates acute kidney injury by disturbing the activation of CD5L/apoptosis inhibitor of macrophage (AIM) protein. PLoS One. 2021;16(11):e0260449
• All: 3 reference(s)