Erg^tm1.2Btp
Targeted Allele Detail

Summary

• Symbol: Erg^tm1.2Btp
• Name: ETS transcription factor; targeted mutation 1.2, Bo Torben Porse
• MGI ID: MGI:7407252
• Synonyms: Erg^delta
• Gene: Erg Location: Chr16:95160028-95387452 bp, - strand Genetic Position: Chr16, 56.04 cM
• Alliance: Erg^tm1.2Btp page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:331735
• Parent Cell Line: E14.1 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: Exon 11 was flanked with loxP sites. The inserted FRT-flanked neomycin stop cassette was removed via flp-mediated recombination. Exon 11 was deleted via cre-mediated recombination in the germline. (J:331735)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Erg Mutation: 28 strains or lines available

References

• Original: J:331735 Knudsen KJ, et al., ERG promotes the maintenance of hematopoietic stem cells by restricting their differentiation. Genes Dev. 2015 Sep 15;29(18):1915-29
• All: 1 reference(s)