Klf5^tm1Mema
Targeted Allele Detail

Summary

• Symbol: Klf5^tm1Mema
• Name: Kruppel-like transcription factor 5; targeted mutation 1, Masatsugu Ema
• MGI ID: MGI:7407175
• Synonyms: Klf5^flox
• Gene: Klf5 Location: Chr14:99536127-99550848 bp, + strand Genetic Position: Chr14, 49.43 cM, cytoband E2.1
• Alliance: Klf5^tm1Mema page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:245724
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Exons 2 and 3 were flanked by loxP sites. (J:245724)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Klf5 Mutation: 38 strains or lines available

References

• Original: J:245724 Azami T, et al., Klf5 maintains the balance of primitive endoderm versus epiblast specification during mouse embryonic development by suppression of Fgf4. Development. 2017 Oct 15;144(20):3706-3718
• All: 2 reference(s)