Ythdf2^tm1.1Sjj
Targeted Allele Detail

Summary

• Symbol: Ythdf2^tm1.1Sjj
• Name: YTH N6-methyladenosine RNA binding protein 2; targeted mutation 1.1, Sheng-Jian Ji
• MGI ID: MGI:7398464
• Synonyms: Ythdf2^fl
• Gene: Ythdf2 Location: Chr4:131912227-131939567 bp, - strand Genetic Position: Chr4, 64.92 cM
• Alliance: Ythdf2^tm1.1Sjj page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:331737
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: A loxP site and an FRT-flanked neomycin resistance gene cassette coupled with a loxP site were inserted in intron 3 and intron 4, respectively. The FRT-flanked neomycin selection cassette was removed via FLP-mediated recombination in the germline. (J:331737)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ythdf2 Mutation: 32 strains or lines available

References

• Original: J:331737 Yu J, et al., The m(6) A Readers YTHDF1 and YTHDF2 Synergistically Control Cerebellar Parallel Fiber Growth by Regulating Local Translation of the Key Wnt5a Signaling Components in Axons. Adv Sci (Weinh). 2021 Nov;8(22):e2101329
• All: 4 reference(s)