Gt(ROSA)26Sor^{em1(CAG-Cdh1)Vks}
Endonuclease-mediated Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^{em1(CAG-Cdh1)Vks}
• Name: gene trap ROSA 26, Philippe Soriano; endonuclease-mediated mutation 1, Venkataramana K Sidhaye
• MGI ID: MGI:7388566
• Synonyms: Cdh1^Oe
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^{em1(CAG-Cdh1)Vks} page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready, Inserted expressed sequence)
• Mutation: Insertion
• CRISPR-targeting inserted a CAG promoter, floxed STOP cassette, and mouse coding sequence. (J:330959)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 956 strains or lines available

References

• Original: J:330959 Ghosh B, et al., Loss of E-cadherin is causal to pathologic changes in chronic lung disease. Commun Biol. 2022 Oct 29;5(1):1149
• All: 1 reference(s)