Igs43^{tm1.1(Nfe2l2-luc2,-tdTomato)Top}
Targeted Allele Detail

Summary

• Symbol: Igs43^{tm1.1(Nfe2l2-luc2,-tdTomato)Top}
• Name: intergenic site 43; targeted mutation 1.1, TOP Transgenic Operative Products Srl
• MGI ID: MGI:7388153
• Synonyms: Tg(RrARE-luc2,-tdTomato)Top
• Gene: Igs43 Location: unknown Genetic Position: Chr1, Syntenic
• Alliance: Igs43^{tm1.1(Nfe2l2-luc2,-tdTomato)Top} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:250245
• Parent Cell Line: v6.4 (ES Cell)
• Strain of Origin: (C57BL/6J x 129S4/SvJae)F1

Mutation description

• Allele Type: Targeted (Reporter)
• Mutation: Insertion
• Mutation details: The targeting construct inserted into a neutral location in chromosome 1 an antioxidant responsive element (minimal Nfe2l2 promoter; four selected Nfe2l2 responsive elements repeated twice), luciferase reporter gene, and tdTomato reporter gene. Cre-mediated recombination removed the floxed stop cassette. (J:250245)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Igs43 Mutation: 0 strains or lines available

References

• Original: J:250245 Rizzi N, et al., Identification of novel loci for the generation of reporter mice. Nucleic Acids Res. 2017 Apr 07;45(6):e37
• All: 3 reference(s)