Gramd1a^em1Pton
Endonuclease-mediated Allele Detail

Summary

• Symbol: Gramd1a^em1Pton
• Name: GRAM domain containing 1A; endonuclease-mediated mutation 1, Peter Tontonoz
• MGI ID: MGI:7386913
• Gene: Gramd1a Location: Chr7:30829552-30855321 bp, - strand Genetic Position: Chr7, 19.3 cM
• Alliance: Gramd1a^em1Pton page

Mutation origin

• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting deleted exon 2 through intron 4 to produce a frameshift mutation. (J:297019)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gramd1a Mutation: 34 strains or lines available

References

• Original: J:297019 Ferrari A, et al., Aster Proteins Regulate the Accessible Cholesterol Pool in the Plasma Membrane. Mol Cell Biol. 2020 Sep 14;40(19)
• All: 1 reference(s)