Krtap1-3^em1(IMPC)J
Endonuclease-mediated Allele Detail

Summary

• Symbol: Krtap1-3^em1(IMPC)J
• Name: keratin associated protein 1-3; endonuclease-mediated mutation 1, Jackson
• MGI ID: MGI:7385113
• Gene: Krtap1-3 Location: Chr11:99481287-99482165 bp, - strand Genetic Position: Chr11, 62.94 cM
• Alliance: Krtap1-3^em1(IMPC)J page
• IMPC: Krtap1-3 gene page

Mutation origin

• Strain of Origin: C57BL/6NJ
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences AATGGGATGAATTCCAACAG and GCCAGGGATTATAAAAAGAC, which resulted in a 1322 bp deletion beginning at Chromosome 11 position 99,590,083 bp and ending after 99,591,404 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000665082 (exon 1) and 443 bp of flanking intronic sequence including the start site, splice acceptor and donor and is predicted to result in a null allele. (J:188991)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Krtap1-3 Mutation: 7 strains or lines available

References

• Original: J:188991 The Jackson Laboratory, Alleles produced for the KOMP project by The Jackson Laboratory. MGI Direct Data Submission. 2012
• All: 1 reference(s)