Tg(Or55b4,-MAPT/EGFP)U16Juhi
Transgene Detail

Summary

• Symbol: Tg(Or55b4,-MAPT/EGFP)U16Juhi
• Name: transgene insertion U16, Junji Hirota
• MGI ID: MGI:7384843
• Synonyms: Tg-U16
• Transgene: Tg(Or55b4,-MAPT/EGFP)U16Juhi Location: unknown
• Alliance: Tg(Or55b4,-MAPT/EGFP)U16Juhi page

Transgene origin

• Strain of Origin: Not Applicable

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence, Reporter)
• Mutation: Insertion
• Tg(Or55b4,-MAPT/EGFP)U16Juhi expresses 5 genes
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  cattle	MAPT (281296)	5' end fused to EGFP
  mouse	Or55b3 (MGI:3030377)
  mouse	Or55b4 (MGI:3030378)
  mouse	Or55b10 (MGI:3030379)
  mouse	Rrm1 (MGI:98180)

• Mutation details: IRES sequence, followed by microtubule-associated protein tau sequence coding for the N-terminal bovine MAPT sequence in-frame with the EGFP fluorescent reporter gene coding region, was inserted in the 3' UTR of the Or55b4 gene in BAC RP23-61O11. The BAC was shortened at the 3' end to only include 16 kb sequence upstream of the Or55b4 transcription start site. The BAC also contains Or55b3, Or55b10, the 3' end of Stim1, and Rrm1. (J:254398)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:254398 Iwata T, et al., A long-range cis-regulatory element for class I odorant receptor genes. Nat Commun. 2017 Oct 12;8(1):885
• All: 1 reference(s)