Tg(Sftpc-EGFR)1Takt
Transgene Detail

Summary

• Symbol: Tg(Sftpc-EGFR)1Takt
• Name: transgene insertion 1, Takashi Takahashi
• MGI ID: MGI:7382952
• Transgene: Tg(Sftpc-EGFR)1Takt Location: unknown
• Alliance: Tg(Sftpc-EGFR)1Takt page

Transgene origin

• Strain of Origin: C57BL/6J

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Sftpc-EGFR)1Takt expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  EGFR (1956)

  Egfr	(MGI:95294)

• Mutation details: The transgene contains the promoter driving lung-specific expression of a human EGFR construct lacking residues 746-750. (J:305973)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:305973 Isomura H, et al., Conditional Ror1 knockout reveals crucial involvement in lung adenocarcinoma development and identifies novel HIF-1alpha regulator. Cancer Sci. 2021 Apr;112(4):1614-1623
• All: 1 reference(s)