Cma1^{em1(Hbegf)Nsas}
Endonuclease-mediated Allele Detail

Summary

• Symbol: Cma1^{em1(Hbegf)Nsas}
• Name: chymase 1, mast cell; endonuclease-mediated mutation 1, Nobuya Sasaki
• MGI ID: MGI:7382767
• Synonyms: Mcpt5/Cma1^DTR
• Gene: Cma1 Location: Chr14:56178908-56182132 bp, - strand Genetic Position: Chr14, 28.19 cM
• Alliance: Cma1^{em1(Hbegf)Nsas} page

Mutation origin

• Strain of Origin: (C57BL/6 x DBA/2)F1

Mutation description

• Allele Type: Endonuclease-mediated (Inserted expressed sequence)
• Mutation: Insertion
• Cma1^{em1(Hbegf)Nsas} expresses 1 gene
  Knock-in expresses:
  

  Organism	Expressed Gene	Note
  Not Specified	Hbegf

• HBEGF knockin mice at the translation initiation codon of the gene. (J:305529)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Cma1 Mutation: 26 strains or lines available

References

• Original: J:305529 Sasaki H, et al., New inducible mast cell-deficient mouse model (Mcpt5/Cma1(DTR)). Biochem Biophys Res Commun. 2021 Apr 30;551:127-132
• All: 1 reference(s)