Gnai3^em1Btar
Endonuclease-mediated Allele Detail

Summary

• Symbol: Gnai3^em1Btar
• Name: G protein subunit alpha i3; endonuclease-mediated mutation 1, Basile Tarchini
• MGI ID: MGI:7380594
• Synonyms: Gnai3^EGFP
• Gene: Gnai3 Location: Chr3:108014596-108053462 bp, - strand Genetic Position: Chr3, 46.83 cM
• Alliance: Gnai3^em1Btar page

Mutation origin

• Strain of Origin: Not Applicable

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout, Reporter)
• Mutation: Insertion
• Mutation details: This allele expresses an Gnai3/EGFP fusion protein. An Egfp cDNA was inserted in frame at the sequences encoding the C-terminal end of the gene in exon 8. (J:330604)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gnai3 Mutation: 30 strains or lines available

References

• Original: J:330604 Akturk A, et al., RGS12 polarizes the GPSM2-GNAI complex to organize and elongate stereocilia in sensory hair cells. Sci Adv. 2022 Oct 21;8(42):eabq2826
• All: 1 reference(s)