Maf^tm2.2Cbm
Targeted Allele Detail

Summary

• Symbol: Maf^tm2.2Cbm
• Name: MAF bZIP transcription factor; targeted mutation 2.2, Carmen Birchmeier
• MGI ID: MGI:7380444
• Gene: Maf Location: Chr8:116429992-116433633 bp, - strand Genetic Position: Chr8, 62.61 cM
• Alliance: Maf^tm2.2Cbm page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:272610
• Parent Cell Line: E14.1 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A loxP site was inserted upstream of the coding region. An FRT-flanked neo cassette with a 5' loxP site was inserted downstream of the open reading frame. Flp-mediated recombination removed the neo cassette. Cre-mediated recombination removed the codind sequence. (J:272610)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Maf Mutation: 27 strains or lines available

References

• Original: J:272610 Kim M, et al., Maf links Neuregulin1 signaling to cholesterol synthesis in myelinating Schwann cells. Genes Dev. 2018 May 1;32(9-10):645-657
• All: 1 reference(s)