Tg(Nppa-lacZ)r-0.7Vmc
Transgene Detail

Summary

• Symbol: Tg(Nppa-lacZ)r-0.7Vmc
• Name: transgene insertion r-0.7, Vincent M Christoffels
• MGI ID: MGI:7378835
• Synonyms: -0.7rLacZ, ANF-nlacZ
• Transgene: Tg(Nppa-lacZ)r-0.7Vmc Location: unknown
• Alliance: Tg(Nppa-lacZ)r-0.7Vmc page

Transgene origin

• Strain of Origin: FVB

Transgene description

• Transgene Type: Transgenic (Reporter)
• Mutation: Insertion
• Mutation details: The 638/+70 bp rat Nppa regulatory region sequence, containing the promoter and silencer and enhancer sequences, is placed upstream of a beta-globin/IgG chimeric intron, nls sequence, the lacZ beta-galactosidase gene and bovine GH poly(A) signal sequence. The regulatory sequence drives expression in the embryonic atrial and ventricular chamber myocardium. (J:76656)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:76656 Habets PE, et al., Cooperative action of Tbx2 and Nkx2.5 inhibits ANF expression in the atrioventricular canal: implications for cardiac chamber formation. Genes Dev. 2002 May 15;16(10):1234-46
• All: 2 reference(s)