About   Help   FAQ
Tns3em1Cpar
Endonuclease-mediated Allele Detail
Summary
Symbol: Tns3em1Cpar
Name: tensin 3; endonuclease-mediated mutation 1, Carlos Parras
MGI ID: MGI:7378787
Synonyms: Tns3Flox
Gene: Tns3  Location: Chr11:8381652-8614681 bp, - strand  Genetic Position: Chr11, 4.99 cM
Alliance: Tns3em1Cpar page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:330512
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Endonuclease-mediated (Conditional ready)
Mutation:    Insertion
 
Mutation detailsCRISPR-targeting introduced the insertion of the loxP sites flanking the exon 9 of the Tns3 in mouse embryonic stem cells (ES cells). (J:330512)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tns3 Mutation:  554 strains or lines available
Notes
Lentiviral gene trap injected into zygotes.
References
Original:  J:330512 Merour E, et al., Transient regulation of focal adhesion via Tensin3 is required for nascent oligodendrocyte differentiation. Elife. 2022 Oct 10;11:e80273
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/25/2025
MGI 6.24
The Jackson Laboratory