Brca2^em1Nki
Endonuclease-mediated Allele Detail

Summary

• Symbol: Brca2^em1Nki
• Name: breast cancer 2, early onset; endonuclease-mediated mutation 1, The Netherlands Cancer Institute
• MGI ID: MGI:7378470
• Gene: Brca2 Location: Chr5:150446095-150493794 bp, + strand Genetic Position: Chr5, 89.52 cM
• Alliance: Brca2^em1Nki page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutations: Intragenic deletion, Single point mutation
• Mutation details: CRISPR-targeting of exon 11 deleted nucleotide 5805(T) and introduced a silent mutation A1934 GCA to GCC. (J:82809)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Brca2 Mutation: 131 strains or lines available

References

• Original: J:82809 European Mouse Mutant Archive, Information obtained from the European Mouse Mutant Archive (EMMA). Unpublished. 2003-2013
• All: 1 reference(s)