Tnn^em1Bcgen
Endonuclease-mediated Allele Detail

Summary

• Symbol: Tnn^em1Bcgen
• Name: tenascin N; endonuclease-mediated mutation 1, Biocytogen LLC
• MGI ID: MGI:7378462
• Synonyms: Tnn KO
• Gene: Tnn Location: Chr1:159912599-159981150 bp, - strand Genetic Position: Chr1, 69.4 cM
• Alliance: Tnn^em1Bcgen page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: CRISPR-targeting non-conservative regions within Intron 1-2 and Intron 4-5 of Tnn to knock out Exon 2-4. (J:330387)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tnn Mutation: 91 strains or lines available

References

• Original: J:330387 Lu F, et al., TNN is first linked to auditory neuropathy. Biochem Biophys Res Commun. 2022 Dec 3;632:69-75
• All: 1 reference(s)