Gigyf1^em1Gpt
Endonuclease-mediated Allele Detail

Summary

• Symbol: Gigyf1^em1Gpt
• Name: GRB10 interacting GYF protein 1; endonuclease-mediated mutation 1, GemPharmatech Co., Ltd
• MGI ID: MGI:7367246
• Synonyms: Gigyf1^f
• Gene: Gigyf1 Location: Chr5:137516810-137526197 bp, + strand Genetic Position: Chr5, 76.53 cM
• Alliance: Gigyf1^em1Gpt page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready)
• Mutation: Insertion
• Mutation details: CRISPR/cas9 mediated recombination introduced loxP sites flanking the genomic region encoding exons 1 through 9. (J:329929)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gigyf1 Mutation: 29 strains or lines available

References

• Original: J:329929 Chen G, et al., GIGYF1 disruption associates with autism and impaired IGF-1R signaling. J Clin Invest. 2022 Oct 3;132(19):e159806
• All: 1 reference(s)