Aff4^em1Bcgen
Endonuclease-mediated Allele Detail

Summary

• Symbol: Aff4^em1Bcgen
• Name: AF4/FMR2 family, member 4; endonuclease-mediated mutation 1, Biocytogen LLC
• MGI ID: MGI:7356584
• Synonyms: Aff4^fl
• Gene: Aff4 Location: Chr11:53241660-53312657 bp, + strand Genetic Position: Chr11, 31.93 cM
• Alliance: Aff4^em1Bcgen page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready, No functional change)
• Mutation: Insertion
• Exons 2 and 3 were flanked by loxP sites using CRISPR/Cas9 technology. (J:330041)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Aff4 Mutation: 92 strains or lines available

References

• Original: J:330041 Chen Y, et al., AFF4 regulates cellular adipogenic differentiation via targeting autophagy. PLoS Genet. 2022 Sep;18(9):e1010425
• All: 1 reference(s)