Vgll4^tm1.1Linzh
Targeted Allele Detail

Summary

• Symbol: Vgll4^tm1.1Linzh
• Name: vestigial like family member 4; targeted mutation 1.1, Zhiqiang Lin
• MGI ID: MGI:7344373
• Synonyms: Vgll4^fl
• Gene: Vgll4 Location: Chr6:114837589-114946955 bp, - strand Genetic Position: Chr6, 53.07 cM
• Alliance: Vgll4^tm1.1Linzh page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:329315
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: A loxP site was introduced upstream of exon 5 and a second loxP site and FRT flanked neo cassette were inserted downstream of exon 5 via homologous recombination. F;p-mediated recombination removed the neo cassette. (J:329315)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Vgll4 Mutation: 24 strains or lines available

References

• Original: J:329315 Sheldon C, et al., Depletion of VGLL4 Causes Perinatal Lethality without Affecting Myocardial Development. Cells. 2022 Sep 10;11(18)
• All: 1 reference(s)