Vgll4^em1Linzh
Endonuclease-mediated Allele Detail

Summary

• Symbol: Vgll4^em1Linzh
• Name: vestigial like family member 4; endonuclease-mediated mutation 1, Zhiqiang Lin
• MGI ID: MGI:7344372
• Gene: Vgll4 Location: Chr6:114837589-114946955 bp, - strand Genetic Position: Chr6, 53.07 cM
• Alliance: Vgll4^em1Linzh page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: CRISPR/cas9 mediated recombination using guide NAs targeting the TDU domain created two deletions, one of 34 bp and the other of 12 bp, in exon 5. (J:329315)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Vgll4 Mutation: 24 strains or lines available

References

• Original: J:329315 Sheldon C, et al., Depletion of VGLL4 Causes Perinatal Lethality without Affecting Myocardial Development. Cells. 2022 Sep 10;11(18)
• All: 1 reference(s)