Ino80^tm1Kwo
Targeted Allele Detail

Summary

• Symbol: Ino80^tm1Kwo
• Name: INO80 complex subunit; targeted mutation 1, Jongbum Kwon
• MGI ID: MGI:7341371
• Gene: Ino80 Location: Chr2:119203523-119308168 bp, - strand Genetic Position: Chr2, 59.97 cM, cytoband E5
• Alliance: Ino80^tm1Kwo page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:328904
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129/Sv

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The first three protein-coding exons (exons 2 to 4) were replaced with a PGK-neomycin resistance cassette. (J:328904)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ino80 Mutation: 438 strains or lines available

References

• Original: J:328904 Lee HS, et al., Stabilization and targeting of INO80 to replication forks by BAP1 during normal DNA synthesis. Nat Commun. 2014 Oct 6;5:5128
• All: 2 reference(s)