Map2k6^tm1.1Gsab
Targeted Allele Detail

Summary

• Symbol: Map2k6^tm1.1Gsab
• Name: mitogen-activated protein kinase kinase 6; targeted mutation 1.1, Guadalupe Sabio
• MGI ID: MGI:7339075
• Gene: Map2k6 Location: Chr11:110289948-110416348 bp, + strand Genetic Position: Chr11, 73.6 cM, cytoband E1
• Alliance: Map2k6^tm1.1Gsab page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:249909
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: LoxP sites and a n frt-flanked neomycin selection cassette were inserted to flank exon 2. The selection cassette was removed in the germline via FLP-mediated recombination. (J:249909)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Map2k6 Mutation: 43 strains or lines available

References

• Original: J:249909 Matesanz N, et al., MKK6 controls T3-mediated browning of white adipose tissue. Nat Commun. 2017 Oct 11;8(1):856
• All: 4 reference(s)