Stag2^em#Htyu
Endonuclease-mediated Allele Detail

Summary

• Symbol: Stag2^em#Htyu
• Name: STAG2 cohesin complex component; endonuclease-mediated mutation, Hongtao Yu
• MGI ID: MGI:7335242
• Gene: Stag2 Location: ChrX:41238194-41366062 bp, + strand Genetic Position: ChrX, 23.19 cM, cytoband A2
• Alliance: Stag2^em#Htyu page

Mutation origin

• Strain of Origin: (C57BL/6 x C3H)F1

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: CRISPR/Cas9 technology targeting exon 8 generated deletions of this exon. This record represents pooled data of two lines (Del #1 and Del #2) that were generated deleting exon 8. (J:328115)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Stag2 Mutation: 14 strains or lines available

References

• Original: J:328115 Cheng N, et al., STAG2 promotes the myelination transcriptional program in oligodendrocytes. Elife. 2022 Aug 12;11:e77848
• All: 1 reference(s)